PUBLICATIONS

 

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2021

Goldstein Y, Spitz S, Turjeman K, Selinger F, Barenholz Y, Ertl P, Benny O*, Bavli D*

Breaking the Third Wall: Implementing 3D-Printing Techniques to Expand the Complexity and Abilities of Multi-Organ-on-a-Chip Devices

Micromachines. 2021 May 12, 627

2020

 

Amoyav B, Goldstein Y, Steinberg E, Benny O.

3D Printed Microfluidic Devices for Drug Release Assays.

Pharmaceutics. 2020 Dec 23;13(1):13.

 

Rosenberg S., Steinberg E., Yaacov A., Lutati R., Mordechai A., Linetsky E., Lossos A., Paldor I., Benny O.

Spheroids study of a Glioblastoma Tumor Identified a Subclonal Mutation of EGFR T790M

Neuro-Oncology, 22, Issue Supplement_2, Nov. 2020, Page ii75,

Esa R, Steinberg E, Dror D, Schwob O, Khajavi M, Maoz M, Kinarty Y, Inbal A, Zick A, Benny O.

The Role of Methionine Aminopeptidase 2 in Lymphangiogenesis.
Int J Mol Sci. 2020 Jul 21;21(14):5148. doi: 10.3390/ijms21145148.

 

Steinberg E*, Orehov N*, Tischenko K, Schwob O, Zamir G, Hubert A, Manevitch Z, Benny O.

Rapid Clearing for High Resolution 3D Imaging of Ex Vivo Pancreatic Cancer Spheroids.

Int J Mol Sci. 2020 Oct 18;21(20):E7703

 

Fluksman A., Steinberg E., Orehov N., Shai E., Lahiani A., Katzhendler J., Marcinkiewicz C., Lazarovici P., Benny O.

Integrin α2β1 Targeted Self-Assembled Nanocarriers for Tumor Bioimaging.

ACS Appl. Bio Mater. 2020, 3, 9

 

Esa R, Steinberg E, Dror D, Schwob O, Khajavi M, Maoz M, Kinarty Y, Inbal A, Zick A, Benny O.

The Role of Methionine Aminopeptidase 2 in Lymphangiogenesis.

Int J Mol Sci. 2020 Jul 21;21(14):5148.

 

Brill-Karniely Y.*, Dror D.*, Duanis-Assaf T., Goldstein Y., Schwob O., Millo T., Orehov N., Stern T., Jaber M., Loyfer N. Vosk R., Benyamini H., Bielenberg D., Kaplan T., Buganim Y, Reches M., Benny O.

Triangular Correlation (TrC) between cancer aggressiveness, cell uptake capability and cell deformability.

Science Advances, 2020, Vol. 6, no. 3, eaax2861.

 

2019

Karsch-Bluman A., Avraham S., Assayag M., Schwob O. and Benny O.

Encapsulated Carbenoxolone Reduces Lung Metastases.

Cancers 2019, 11(9), 1383

 

Amoyav B, Benny O.

Microfluidic Based Fabrication and Characterization of Highly Porous Polymeric Microspheres.

Polymers. 2019 Mar 5;11(3). pii: E419

 

Abramov E., Schwob O, Benny O.

Film‐ and ointment‐based delivery systems for the transdermal delivery of TNP‐470

Polym. Adv. Technol. 2019 30:10: 2586-2595

 

Karsch-Bluman A, Feiglin A, Arbib E, Stern T, Shoval H, Schwob O, Berger M, Benny O.

Tissue Necrosis and Its Role in Cancer Progression.

Oncogene. 2019 Mar;38(11):1920-1935.

 

2018

Ella E, Harel Y, Abraham M, Wald H, Benny O, Karsch-Bluman A, Vincent D, Laurent D, Amir G, Izhar U, Shapira OM, Yoon D, Lee HS, Sugarbaker DJ, Burt B, Peled A, Wald O. 

Matrix metalloproteinase 12 promotes tumor propagation in the lung.

J Thorac Cardiovasc Surg. 2018 May;155(5):2164-2175

 

Lazarovici P., Lahiani A., Gincberg G., Haham D., Fluksman A., Benny O., Marcinkiewicz C., Lelkes PI.

Nerve Growth Factor-Induced Angiogenesis: 1. Endothelial Cell Tube Formation Assay.

Methods Mol Biol. 2018;1727:239-250

 Benzion A. and Benny O.,

Body on Chip-A Distant Dream or an Emerging Reality?

Drug Des Int Prop Int J. 2018; 1(4)

2017

Ehrenberg M, Benny O.

Evolving multidimensional pharmacological approaches to CNV therapy in AMD.

Curr Eye Res. 2017 Nov 7:1-8.

 

Shoval H, Karsch-Bluman A, Brill-Karniely Y, Stern T, Zamir G, Hubert A, Benny O. 

Tumor cells and their crosstalk with endothelial cells in 3D spheroids.

Sci Rep. 2017 Sep 5;7(1):10428.

 

Karsch-Bluman A, Amoyav B, Friedman N, Shoval H, Schwob O, Ella E, Wald O, Benny O.

High mobility group box 1 antagonist limits metastatic seeding in the lungs via reduction of cell-cell adhesion.

Oncotarget. 2017 May 16;8(20):32706-32721.

 

Larush L, Kaner I, Fluksman A, Tamsut A, Ashok Pawar A, Lesnovski P, Benny O, Magdassi S.

3D printing of responsive hydrogels for drug-delivery systems. 

J of 3D Printing in Medicine. 2017 Oct; Vol. 1, No. 4,

 

Stern T, Kaner I, Laser Zer N, Shoval H, Dror D, Manevitch Z, Chai L, Brill-Karniely Y, Benny O.

Rigidity of polymer micelles affects interactions with tumor cells.

J Control Release. 2017 Jul 10;257:40-50.

 

Abramov E, Schwob O, Benny O.

Analytical Method for Transdermal Delivery of the Anti-angiogenic Compound TNP-470.

J Anal Bioanal Tech. 2017 May 24; 8:365.

 

2016

Licht T, Rothe G, Kreisel T, Wolf B, Benny O, Rooney AG, Ffrench-Constant C, Enikolopov G, Keshet E.

VEGF preconditioning leads to stem cell remodeling and attenuates age-related decay of adult hippocampal neurogenesis.

Proc Natl Acad Sci U S A. 2016 Nov 29;113(48):E7828-E7836.

 

Ehrenberg M, Ehrenberg S, Schwob O, Benny O.

Murine fundus fluorescein angiography: An alternative approach using a handheld camera.

Exp Eye Res. 2016 Jul;148:74-78.

 

2015

Abramov E, Cassiola F, Schwob O, Karsh-Bluman A, Shapero M, Ellis J, Luyindula D, Adini I, D'Amato RJ, Benny O.

Cellular mechanism of oral absorption of solidified polymer micelles.

Nanomedicine. 2015 Nov;11(8):1993-2002.

2014

 Birsner AE*, Benny O*, D'Amato RJ.

The corneal micropocket assay: a model of angiogenesis in the mouse eye.

J Vis Exp. 2014 Aug 16;(90).

 

Momic T, Katzehendler J, Benny O, Lahiani A, Cohen G, Noy E, Senderowitz H, Eble JA, Marcinkiewicz C, Lazarovici P.

Vimocin and vidapin, cyclic KTS peptides, are dual antagonists of α1β1/α2β1 integrins with antiangiogenic activity.

J Pharmacol Exp Ther. 2014 Sep;350(3):506-19.

 

Adini I, Ghosh K, Adini A, Chi ZL, Yoshimura T, Benny O, Connor KM, Rogers MS, Bazinet L, Birsner AE, Bielenberg DR, D'Amato RJ.

Melanocyte-secreted fibromodulin promotes an angiogenic microenvironment.

J Clin Invest. 2014 Jan;124(1):425-36.

 

2013

Panigrahy D, Kalish BT, Huang S, Bielenberg DR, Le HD, Yang J, Edin ML, Lee CR, Benny O, Mudge DK, Butterfield CE, Mammoto A, Mammoto T, Inceoglu B, Jenkins RL, Simpson MA, Akino T, Lih FB, Tomer KB, Ingber DE, Hammock BD, Falck JR, Manthati VL, Kaipainen A, D'Amore PA, Puder M, Zeldin DC, Kieran MW.

Epoxyeicosanoids promote organ and tissue regeneration.

Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13528-33.

 

Yoshimura T*, Benny O*, Bazinet L, D'Amato RJ.

Suppression of autoimmune retinal inflammation by an antiangiogenic drug.

PLoS One. 2013 Jun 13;8(6):e66219.

 

Adini A, Adini I, Ghosh K, Benny O, Pravda E, Hu R, Luyindula D, D'Amato RJ.

The stem cell marker prominin-1/CD133 interacts with vascular endothelial growth factor and potentiates its action.

Angiogenesis. 2013 Apr;16(2):405-16.

 

2012

Panigrahy D, Edin ML, Lee CR, Huang S, Bielenberg DR, Butterfield CE, Barnés CM, Mammoto A, Mammoto T, Luria A, Benny O, Chaponis DM, Dudley AC, Greene ER, Vergilio JA, Pietramaggiori G, Scherer-Pietramaggiori SS, Short SM, Seth M, Lih FB, Tomer KB, Yang J, Schwendener RA, Hammock BD, Falck JR, Manthati VL, Ingber DE, Kaipainen A, D'Amore PA, Kieran MW, Zeldin DC.

Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice.

J Clin Invest. 2012 Jan;122(1):178-91.

 

Shulman M1, Cohen M, Soto-Gutierrez A, Yagi H, Wang H, Goldwasser J, Lee-Parsons CW, Benny O, Yarmush ML, Nahmias Y.

Enhancement of naringenin bioavailability by complexation with hydroxypropyl-β-cyclodextrin.

PLoS One. 2011 Apr 6;6(4):e18033.

 

2011

Becker CM, Beaudry P, Funakoshi T, Benny O, Zaslavsky A, Zurakowski D, Folkman J, D'Amato RJ, Ryeom S.

Circulating endothelial progenitor cells are up-regulated in a mouse model of endometriosis.

Am J Pathol. 2011 Apr;178(4):1782-91.

 

2010

Benny O, Nakai K, Yoshimura T, Bazinet L, Akula JD, Nakao S, Hafezi-Moghadam A, Panigrahy D, Pakneshan P, D'Amato RJ.

Broad spectrum antiangiogenic treatment for ocular neovascular diseases.

PLoS One. 2010 Sep 1;5(9). pii: e12515.

 

Arai T, Benny O, Joki T, Menon LG, Machluf M, Abe T, Carroll RS, Black PM.

Novel local drug delivery system using thermoreversible gel in combination with polymeric microspheres or liposomes.

Anticancer Res. 2010 Apr;30(4):1057-64.

2009

Baruch L, Benny O, Gilert A, Ukobnik M, Ben Itzhak O, Machluf M.

Alginate-PLL cell encapsulation system Co-entrapping PLGA-microspheres for the continuous release of anti-inflammatory drugs.

Biomed Microdevices. 2009 Oct;11(5):1103-13.

 

Benny O, Pakneshan P.

Novel technologies for antiangiogenic drug delivery in the brain.

Cell Adh Migr. 2009 Apr-Jun;3(2):224-9. Epub 2009 Apr 6.

 

Benny O, Menon LG, Ariel G, Goren E, Kim SK, Stewman C, Black PM, Carroll RS, Machluf M.

Local delivery of poly lactic-co-glycolic acid microspheres containing imatinib mesylate inhibits intracranial xenograft glioma growth.

Clin Cancer Res. 2009 Feb 15;15(4):1222-31.

 

2008

Fainaru O, Adini I, Benny O, Bazinet L, Pravda E, D'Amato R, Folkman J.

Doxycycline induces membrane expression of VE-cadherin on endothelial cells and prevents vascular hyperpermeability.

FASEB J. 2008 Oct;22(10):3728-35.

 

Benny O, Fainaru O, Adini A, Cassiola F, Bazinet L, Adini I, Pravda E, Nahmias Y, Koirala S, Corfas G, D'Amato RJ, Folkman J.

An orally delivered small-molecule formulation with antiangiogenic and anticancer activity.

Nat Biotechnol. 2008 Jul;26(7):799-807. (Journal Cover).

 

Nakai K, Fainaru O, Bazinet L, Pakneshan P, Benny O, Pravda E, Folkman J, D'Amato RJ.

Dendritic cells augment choroidal neovascularization.

Invest Ophthalmol Vis Sci. 2008 Aug;49(8):3666-70.

 

Benny O, Kim SK, Gvili K, Radzishevsky IS, Mor A, Verduzco L, Menon LG, Black PM, Machluf M, Carroll RS.

In vivo fate and therapeutic efficacy of PF-4/CTF microspheres in an orthotopic human glioblastoma model.

FASEB J. 2008 Feb;22(2):488-99.

 

Fainaru O, Adini A, Benny O, Adini I, Short S, Bazinet L, Nakai K, Pravda E, Hornstein MD, D'Amato RJ, Folkman J.

Dendritic cells support angiogenesis and promote lesion growth in a murine model of endometriosis.

FASEB J. 2008 Feb;22(2):522-9.

 

2007

Duvshani-Eshet M, Benny O, Morgenstern A, Machluf M.

Therapeutic ultrasound facilitates antiangiogenic gene delivery and inhibits prostate tumor growth.

Mol Cancer Ther. 2007 Aug;6(8):2371-82.

 

Gvili K, Benny O, Danino D, Machluf M.

Poly(D,L-lactide-co-glycolide acid) nanoparticles for DNA delivery: waiving preparation complexity and increasing efficiency.

Biopolymers. 2007 Apr 5-15;85(5-6):379-91.

 

2005

Benny O, Duvshani-Eshet M, Cargioli T, Bello L, Bikfalvi A, Carroll RS, Machluf M.

Continuous delivery of endogenous inhibitors from poly(lactic-co-glycolic acid) polymeric microspheres inhibits glioma tumor growth.

Clin Cancer Res. 2005 Jan 15;11(2 Pt 1):768-76.

 

2003

Seagal J, Edry E, Keren Z, Leider N, Benny O, Machluf M, Melamed D.

A fail-safe mechanism for negative selection of isotype-switched B cell precursors is regulated by the Fas/FasL pathway.

J Exp Med. 2003 Nov 17;198(10):1609-19.