Amoyav B, Goldstein Y, Steinberg E, Benny O.

3D Printed Microfluidic Devices for Drug Release Assays.

Pharmaceutics. 2020 Dec 23;13(1):13. doi: 10.3390/pharmaceutics13010013.

Steinberg E, Fluksman A, Zemmour C, Tischenko K, Karsch-Bluman A, Brill-Karniely Y, Birsner AE, D'Amato RJ, Benny O.

Low dose amiodarone reduces tumor growth and angiogenesis.

Sci Rep. 2020 Oct 22;10(1):18034. doi: 10.1038/s41598-020-75142-1.

 Steinberg E*, Orehov N*, Tischenko K, Schwob O, Zamir G, Hubert A, Manevitch Z, Benny O.

Rapid Clearing for High Resolution 3D Imaging of Ex Vivo Pancreatic Cancer Spheroids.

Int J Mol Sci. 2020 Oct 18;21(20):E7703

Fluksman A., Steinberg E., Orehov N., Shai E., Lahiani A., Katzhendler J., Marcinkiewicz C., Lazarovici P., Benny O.

Integrin α2β1‑Targeted Self-Assembled Nanocarriers for Tumor Bioimaging

ACS Appl. Bio Mater. 2020,

Esa R, Steinberg E, Dror D, Schwob O, Khajavi M, Maoz M, Kinarty Y, Inbal A, Zick A, Benny O.

The Role of Methionine Aminopeptidase 2 in Lymphangiogenesis.

Int J Mol Sci. 2020 Jul 21;21(14):5148.


Brill-Karniely Y.*, Dror D.*, Duanis-Assaf T., Goldstein Y., Schwob O., Millo T., Orehov N., Stern T., Jaber M., Loyfer N. Vosk R., Benyamini H., Bielenberg D., Kaplan T., Buganim Y, Reches M., Benny O.

Triangular Correlation (TrC) between cancer aggressiveness, cell uptake capability and cell deformability

Science Advances, 2020, Vol. 6, no. 3, eaax2861

Karsch-Bluman A. , Benny O. 

Necrosis in the Tumor Microenvironment and Its Role in Cancer Recurrence

Adv Exp Med Biol. 2020;1225:89-98


Karsch-Bluman A. , Avraham S., Assayag M., Schwob O. and Benny O. 

Encapsulated Carbenoxolone Reduces Lung Metastases.

Cancers 2019, 11(9), 1383

Amoyav B, Benny O.

Microfluidic Based Fabrication and Characterization of Highly Porous Polymeric Microspheres.

Polymers. 2019 Mar 5;11(3). pii: E419

Karsch-Bluman A, Feiglin A, Arbib E, Stern T, Shoval H, Schwob O, Berger M, Benny O.

Tissue Necrosis and Its Role in Cancer Progression.

Oncogene. 2019 Mar;38(11):1920-1935. 

Fluksman A, Benny O.

A robust method for critical micelle concentration determination using coumarin-6 as a fluorescent probe.

Analytical Methods 2019 v.11 no.30 pp. 3810-3818

Abramov E., Schwob O., Benny O. 

Film and ointment based delivery systems for the transdermal delivery of TNP-470.

Polymers for Advanced Technologies.June 2019. 30(4)·2586-2595


Amoyav, B. &  Benny, O.

Body on Chip-A Distant Dream or an Emerging Reality?

Drug Des Int Prop Int J 1(4)- 2018. DDIPIJ.MS.ID.000118.


Ella E, Harel Y, Abraham M, Wald H, Benny O, Karsch-Bluman A, Vincent D, Laurent D, Amir G, Izhar U, Shapira OM, Yoon D, Lee HS, Sugarbaker DJ, Burt B, Peled A, Wald O.

Matrix metalloproteinase 12 promotes tumor propagation in the lung.

J Thorac Cardiovasc Surg. 155(5):2164-2175.e1. May 2018


Amoyav, B. & Benny, O.

Controlled and tunable polymer particles’ production using a single microfluidic device.

Appl Nanosci April 2018.


Lazarovici P, Lahiani A, Gincberg G, Haham D, Fluksman A, Benny O, Marcinkiewicz C, Lelkes PI.

Nerve Growth Factor-Induced Angiogenesis: 1. Endothelial Cell Tube Formation Assay.

Methods Mol Biol. 1727:239-250. doi: 10.1007/978-1-4939-7571-6_18. 2018


Ehrenberg M, Benny O.

Evolving multidimensional pharmacological approaches to CNV therapy in AMD.

Curr Eye Res. 2018 Feb;43(2):147-154. doi: 10.1080/02713683.2017.1385088. 2018



Larush L, Kaner I, Fluksman A, Tamsut A, Pawar AA, Lesnovski P, Benny O & Magdassi S.

3D printing of responsive hydrogels for drug-delivery systems

J. 3D Print. Med. 2017 Oct 1(4), 219–229


Shoval H, Karsch-Bluman A, Brill-Karniely Y, Stern T, Zamir G, Hubert A, Benny O.

Tumor cells and their crosstalk with endothelial cells in 3D spheroids.

Sci Rep. 2017 Sep 5;7(1):10428. doi: 10.1038/s41598-017-10699-y.

Karsch-Bluman A, Amoyav B, Friedman N, Shoval H, Schwob O, Ella E, Wald O, Benny O.

High mobility group box 1 antagonist limits metastatic seeding in the lungs via reduction of cell-cell adhesion.

Oncotarget. 16;8(20):32706-32721. 2017


Stern T*, Kaner I*, Laser Zer N, Shoval H, Dror D, Manevitch Z, Chai L, Brill-Karniely Y, Benny O.

Rigidity of polymer micelles affects interactions with tumor cells. 

J Control Release. pii: S0168-3659(16)30783-0. 2016


Licht T, Rothe G, Kreisel T, Wolf B, Benny O, Rooney AG, Ffrench-Constant C, Enikolopov G, Keshet E.

VEGF preconditioning leads to stem cell remodeling and attenuates age-related decay of adult hippocampal neurogenesis.

Proc Natl Acad Sci U S A. 113(48):E7828-E7836. 2016


Ehrenberg M, Ehrenberg S, Schwob O, Benny O.

Murine fundus fluorescein angiography: An alternative approach using a handheld camera.

Exp Eye Res.Jul;148:74-8. 2016


Abramov E, Cassiola F, Schwob O, Karsh-Bluman A, Shapero M, Ellis J, Luyindula D, Adini I, D'Amato RJ, Benny O. 

Cellular mechanism of oral absorption of solidified polymer micelles.

Nanomedicine 11(8):1993–2002. 2015


Momic T, Katzehendler J, Benny O, Lahiani A, Cohen G, Noy E, Senderowitz H, Eble JA, Marcinkiewicz C, Lazarovici P. 

Vimocin and vidapin, cyclic KTS peptides, are dual antagonists of α1β1/α2β1 integrins with antiangiogenic activity. 

J Pharmacol Exp Ther 350(3):506–519. 2014 


Birsner AE*, Benny O*, D'Amato RJ.

The corneal micropocket assay: a model of angiogenesis in the mouse eye.

J Vis Expo 16 (90). 2014


Adini I, Ghosh K, Adini A, Chi ZL, Yoshimura T, Benny O, Connor KM, Rogers MS, Bazinet L, Birsner AE, Bielenberg DR, D'Amato RJ. 

Melanocyte-secreted fibromodulin promotes an angiogenic microenvironment.

J Clin Invest 124(1):425-436. 2014


Panigrahy D, Kalish BT, Huang S, Bielenberg DR, Le HD, Yang J, Edin ML, Lee CR, Benny O, Mudge DK, Butterfield CE, Mammoto A, Mammoto T, Inceoglu B, Jenkins RL, Simpson MA, Akino T, Lih FB, Tomer KB, Ingber DE, Hammock BD, Falck JR, Manthati VL, Kaipainen A, D'Amore PA, Puder M, Zeldin DC, Kieran MW.

Epoxyeicosanoids promote organ and tissue regeneration.

Proc Natl Acad Sci USA 110(33):13528-13533. 2013


Yoshimura T*, Benny O*, Bazinet L, D'Amato RJ. 

Suppression of autoimmune retinal inflammation by an antiangiogenic drug.

PLoS One 8(6):e66219. 2013


Adini A, Adini I, Ghosh K, Benny O, Pravda E, Hu R, Luyindula D, D'Amato RJ.

The stem cell marker prominin-1/CD133 interacts with vascular endothelial growth factor and potentiates its action.

Angiogenesis 16(2):405-416. 2013


Becker CM, Beaudry P, Funakoshi T, Benny O, Zaslavsky A, Zurakowski D, Folkman J, D'Amato RJ, Ryeom S.

Circulating endothelial progenitor cells are up-regulated in a mouse model of endometriosis.

Am J Pathol 178(4):1782-1791. 2011


Shulman M, Cohen M, Soto-Gutierrez A, Yagi H, Wang H, Goldwasser J, Lee-Parsons CW, Benny O, Yarmush ML, Nahmias Y. 

Enhancement of naringenin bioavailability by complexation with hydroxypropyl-β-cyclodextrin. 

PLoS One 6(4):e18033. 2011


Benny O, Nakai K, Yoshimura T, Bazinet L, Akula JD, Nakao S, Hafezi-Moghadam A, Panigrahy D, Pakneshan P, D'Amato RJ.

Broad spectrum antiangiogenic treatment for ocular neovascular diseases.

PLoS One 5(9):e12515. 2010


Arai T, Benny O, Joki T, Menon LG, Machluf M, Abe T, Carroll RS, Black PM.

Novel local drug delivery system using thermoreversible gel in combination with polymeric microspheres or liposomes.

Anticancer Res 30(4):1057-1064. 2010


Baruch L, Benny O, Gilert A, Ukobnik M, Ben Itzhak O, Machluf M.

Alginate-PLL cell encapsulation system Co-entrapping PLGA-microspheres for the continuous release of anti-inflammatory drugs.

Biomed Microdevices 11(5):1103-1113. 2009


Benny O, Pakneshan P.

Novel technologies for antiangiogenic drug delivery in the brain.

Cell Adh Migr 3(2):224-229. 2009


Benny O, Menon LG, Ariel G, Goren E, Kim SK, Stewman C, Black PM, Carroll RS, Machluf M.

Local delivery of poly lactic-co-glycolic acid microspheres containing imatinib mesylate inhibits intracranial xenograft glioma growth.

Clin Cancer Res 15(4):1222-1231. 2009


Fainaru O, Adini I, Benny O, Bazinet L, Pravda E, D'Amato R, Folkman J.

Doxycycline induces membrane expression of VE-cadherin on endothelial cells and prevents vascular hyperpermeability.

FASEB J 22(10):3728-3735. 2008


Nakai K, Fainaru O, Bazinet L, Pakneshan P, Benny O, Pravda E, Folkman J, D'Amato RJ.

Dendritic cells augment choroidal neovascularization.

Invest Ophthalmol Vis Sci 49(8):3666-3670. 2008


Benny O, Fainaru O, Adini A, Cassiola F, Bazinet L, Adini I, Pravda E, Nahmias Y, Koirala S, Corfas G, D'Amato RJ, Folkman J.

An orally delivered small-molecule formulation with antiangiogenic and anticancer activity.

Nature Biotechnol 26(7):799-807. 2008 JOURNAL COVER


Hilighted: Nat Biotechnol. 2008 Jul;26(7):769-70. .James D, Rabbany S, Rafii S.


Nakai K, Fainaru O, Bazinet L, Pakneshan P, Benny O, Pravda E, Folkman J, D'Amato RJ. 

Dendritic cells support angiogenesis and promote lesion growth in a murine model of endometriosis.

FASEB J 22(2):522-529. 2008


Benny O, Kim SK, Gvili K, Radzishevsky IS, Mor A, Verduzco L, Menon LG, Black PM, Machluf M, Carroll RS.

In vivo fate and therapeutic efficacy of PF-4/CTF microspheres in an orthotopic human glioblastoma model.

FASEB J 22(2):488-499. 2008